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Magnitude of weight loss Phase 2 clinical trial results published in The New England journal of medicine suggest retatrutide may prompt even greater weight loss than other weight-loss medications, including Zepbound
Most commercial insurance plans require prior authorization for GLP-1s used for weight loss, and most demand documentation of BMI plus a prior attempt at structured weight management
Ito et al., 2022)
The duration of storage outside recommended temperature ranges should be documented, and the pharmacy should be consulted about whether the medication remains safe to use based on the specific conditions and duration of improper storage
Kidney Injury: Severe dehydration from excessive vomiting or diarrhea can stress the kidneys
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