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At the end of the day, the option simply comes down to what youre looking to treat

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It's functionally inert

Paradisi R, Fabbri R, Battaglia C, Venturoli S (2013) Ovulatory effects of flutamide in the polycystic ovary syndrome

The insulin signaling pathway, critical for glucose regulation, begins with insulin binding to its receptor, which activates insulin receptor substrates (IRS) and recruits phosphoinositide 3-kinase (PI3 K), which turns phosphatidylinositol-4,5-bisphosphate (PIP 2 ) into phosphatidylinositol-3,4,5-trisphosphat (PIP 3 )