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A study investigated the blood concentrations of various antioxidant defense biomarkers in a group of 80 patients with DM2 to evaluate the potential correlation between antioxidant defense, glycemic control, and the presence of diabetic complications (Nuez-Sells et al., 2019)

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Furthermore, administration of L-carnitine substantially altered the effects of TRZ and markedly reduced the expression of autophagy-related genes such as Beclin1, Autophagy Related Gene 5 (ATG5), and the inflammatory mediator TNF- in comparison to the TRZ treated group (Khedr et al