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The highest concentrations of glucosinolates are found in reproductive organs, including dormant and germinating seeds, developing inflorescences, siliques (fruits), followed by young leaves, roots and mature leaves, which is consistent with the function of glucosinolate-myrosinase system as defensive mechanism in the plant 55,56
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We can change the conformation and function of mutant p53 via pharmacological intervention in specific posttranslational modification pathways