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A 2021 review performed by the nonprofit organization Association for Science in Autism Treatment found that the Brain Balance approach lacks sufficient empirical evidence and should therefore be considered a pseudoscientific treatment. The current program is based on contemporary developmental neuroscience and supported by a modern evidence base developed independently of any former contributors, a Brain Balance representative told The Transmitter

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Ye Z, Hu Q, Zhuo Q, Zhu Y, Fan G, Liu M, et al