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Retrieved from Hathaway, J.T., Shah, M.P., Hathaway, D.B., et al, 3rd (2024)

Efficacy and tolerability outcomes with oral semaglutide were generally consistent regardless of background insulin regimen in PIONEER 8, although AEs (including severe or blood glucose-confirmed hypoglycaemia) were more common with background basal insulin than with premixed or basal-bolus regimens

Enhancing Cognitive Function: Peptide therapy contributes to better memory, sharper focus, and improved cognitive performance

Target genes of interest in the hypothalamus were determined using the Taqman gene expression assay-on-demand TM assays (Applied Biosystems, Foster City, CA) using FAM-labelled probes for target genes and Actb (Mm02619580_g1) and Gapdh (Hs99999905_m1) as reference genes