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They play a crucial role in various cellular processes, including gene expression, DNA repair, metabolism, mitochondrial function, and biogenesis, and have antioxidant activity

After completion, we assessed the credibility of any apparent subgroup effect using the Credibility of Effect Modification Analyses (ICEMAN) tool [25]: (1) health statusNAFLD versus NASH

By reviewing deeper into the mechanism of HO-1 functions, we hope to devise innovative therapeutic measures that are aimed at preventing and curing diabetes-associated cardiovascular complications, ultimately enhancing the well-being and prospects of the patients concerned

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They also note several limitations to the work, including the fact that it was done in mouse models, not humans, and that the mice were all male