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[6] Porpora MG, Brunelli R, Costa G, Imperiale L, Krasnowska EK, Lundeberg T, Nofroni I, Piccioni MG, Pittaluga E, Ticino A, Parasassi T
When XBP1s were co-localized in tumors with hypoxia markers, the loss of XBP1 increased the sensitivity of transformed cells to hypoxia-induced apoptosis and inhibited tumor growth (78)
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The FDA has issued a warning after observing serious liver injury in patients who do not have cirrhosis the very group the drug was intended to help