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According to FDA prescribing information, nausea affects approximately 44% of patients on Wegovy (weight management dose), while vomiting, diarrhea, constipation, and abdominal pain are also common, particularly during dose escalation

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However, an analysis of 966 subjects who received statins in Phase 3 trials of exenatide (51% atorvastatin, 31% simvastatin, 11% pravastatin, 5% lovastatin, 3% fluvastatin) showed comparable lipid-lowering statin effects compared to placebo [20]