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Description

Extracellular Ca 2+ can enter the spine through NMDA receptors (NMDARs) and voltage gated Ca 2+ channels (VGCCs)

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The drugs benefits are clear, but their vast benefits could also be a double-edged sword

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Naltrexone-bupropion is described as an opioid antagonist paired with dopamine and norepinephrine reuptake inhibition, while off-label metformin is framed as working through insulin sensitivity and gut glucose absorption

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Smoking cessation is also beneficial, provided that it does not result in body weight increase [129]

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network hubs, had high energy demands [51, 52]

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