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Study Limitations and Future Research Directions The interpretation of the findings is limited by the small GLP-1RA cohort (n = 12), baseline imbalances in BMI and sex, the single-center retrospective design, incomplete autoantibody testing, and a median follow-up of approximately eight months

however, findings remain inconclusive due to few available trials, small sample sizes, pharmacokinetics and pharmacodynamics analysis, and methodological heterogeneity

In the clinical trial of participants with type 2 diabetes, HbA1c reductions of -1.88% to -2.02% were observed at the 8 mg and 12 mg doses by 24 weeks

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