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However, longer-term data are required to confirm durability of effect, impact on clinical outcomes, and safety over time

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Neuropsychiatry 5 , 100041 (2021)

Chauveau S, Anyukhovsky EP, Ben-Ari M, Naor S, Jiang YP, Danilo P Jr, Rahim T, Burke S, Qiu X, Potapova IA, Doronin SV, Brink PR, Binah O, Cohen IS, Rosen MR (2017) Induced pluripotent stem cell-derived cardiomyocytes provide in vivo biological pacemaker function

Treatment is limited to a maximum of 2 years and should always be accompanied by a reduced-calorie diet and increased physical activity, tailored to individual capabilities and health status