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the wet granules were milled (Co-Mil model 197S, Quadro Corp., Waterloo, Canada), dried in a fluid bed dryer (Glatt, GPCG-1) to a moisture content of not more than 2.0% LOD and the dried granules were passed through a mill (Co-Mil model 197S, Quadro Corp., Waterloo, Canada) and milled to appropriate particle size (geometric mean particle size of about 250 m)

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