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However, unclear chemical components, unverified functional targets and ambiguous molecular mechanisms have hindered the widespread use of TCMP worldwide [5]

This is because not all of the cyanocobalamin can be properly converted to the active form, and the leftover must be flushed out of the body

Vitamin B6 supports protein metabolism and helps regulate the breakdown of carbs and proteins, contributing to overall weight management

The molecule also modulates nitric oxide signaling, dampens local inflammation, supports tendon and ligament repair, and protects gastric mucosa from NSAID injury, which is incidentally why I sometimes pair it with the analgesia plan

While this mechanism remains speculative, the underlying physiology of cryotherapy-induced blood flow changes supports the concept