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In summary, we have determined two glutathione-binding fragments of the GST sequence, and found that the F2 peptide, selected by the CAGF cloning method, can be considered as the inhibitor of GST

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The central clinical idea: when mitochondrial ATP production falls and oxidative stress rises, the brain may lose the energy and antioxidant reserve needed to regulate neurotransmission, maintain cell membranes, recycle methionine, produce SAM, clear adenosine and homocysteine, build glutathione and tolerate medications or supplements

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