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A nested case-control study analyzed data from the French national health care insurance system (SNDS) on individuals with T2D treated with second-line anti-diabetes drugs from 2006 to 2018, reported an increased risk of all thyroid cancer and medullary thyroid cancer with use of GLP-1 agonists after 13 years of treatment 47

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In this randomized, active-controlled clinical study (Study D), pediatric patients (age range 6 to 15 years) with type 1 diabetes (n=349) were treated for 28 weeks with a basal-bolus insulin regimen where regular human insulin was used before each meal