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A peptide with reduced acidity was designed for increased cell permeability The p53 TAD2 sequence exhibited a highly negative charge, whereas the p53 binding interface of the FOXO4 FHD contains several positively charged residues
Use separate syringes for each IM injection
In such structural configuration, the two c-METs are placed in relatively close proximity, which enables their intracellular KDs to undergo autophosphorylation and thus initializing the downstream signaling (Fig
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