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This past summer, the University of North Carolina School of Medicine presented early findings from the first completed randomized controlled trial of semaglutide in 48 people with AUD, which showed that those taking the medication reduced their drinking quantity and their heavy drinking more than a placebo group
GLP-1 medications do not cause stomach paralysis in the clinical sense, though they do slow gastric emptyinga pharmacological effect central to weight loss and blood sugar control
Tirzepatide is a medication that combines the effects of two hormonesglucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)
Clinical evidence shows: 14 to 22% total body weight loss in clinical trials Preferential reduction of visceral (belly) fat over subcutaneous fat Improved insulin sensitivity within 4 to 8 weeks Reduced liver fat (NAFLD improvement) in 60 to 70% of patients Sustained appetite regulation
doi: 10.1016/S0006-8993(00)02741-4 224 BomfimTRForny-GermanoLSathlerLBBrito-MoreiraJHouzelJCDeckerHet al
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