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While the formation of 5-(3,4-dihydroxyphenyl)--valerolactone from (+)-catechin by intestinal bacteria has already been described by Das (79), only more recently the contributing colonic microbiota have been characterized

Current estimates suggest that around 3.6% of adults are clinically deficient, while a much larger group, roughly 12.5%, have low or marginal levels that may still impact health

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