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Depletion of GSH levels necessary for adequate protection to less than 20-30% has been suggested as an explanation of hepatotoxicity of higher doses of compounds such as paracetamol or bromobenzene [13]

COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis

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Tocotrienols are characterized by a chromanol ring attached to an unsaturated isoprenoid side chain, while tocopherols contain a chromanol ring attached to a saturated alkyl side chain