However, there are people on the internet (particularly social media/TikTok/Instagram) that heavily promote/hype it up and get it either through black market or unscrupulous places with no such interventions in conjunction with the GLP-1RA and clearly do not have any indication for GLP-1RAs
10,33 Similarly, the REWIND trial, in patients with T2D and established CVD or cardiovascular risk factors, reported that dulaglutide significantly reduced the incidence of MACE (primary outcome)
Most GLP-1s can be kept at room temperature, below 86F (30C), for a short period, between 14 to 56 days , depending on the specific medication, before they must be discarded Related article: Is Your Semaglutide Safe
Applying those same ingredients to the skin introduces an absorption barrier that has not been validated for this purpose (7,9,10), and no Australia regulator has approved any over-the-counter GLP-1 patch for safety or efficacy
Proteomics Clin Applications (2018) 12(1)