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Although nerve conduction studies or somatosensory evoked potentials can identify abnormalities when the spinal MRI appears normal, their clinical utility in elderly patients is limited, and prompt empirical treatment with vitamin B12 is generally preferable to invasive diagnostic testing

PER1 affects cancer growth and causes an increased rate of ionizing radiation-induced cell death, but it is unclear whether its lack of expression precedes and contributes to cancer development, or is the only source of cancer

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Jan 23 2021;397(10271):319-333