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According to Bernstein, the most common ongoing side effects were nausea, constipation and energy loss (all with 28% of patients reporting experiencing these side effects on an ongoing basis) as well as mood swings (27%), sagging loose skin (25%) and headaches (24%)

11.4 Personalized nutrition, nutrigenomics, and nutrigenetics Given the substantial inter-individual variability in gut microbiota composition, future nutritional strategies are expected to increasingly emphasize dietary personalization tailored to an individuals unique microbial profile

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From a translational standpoint, catestatin may be more tractable as a pathway biomarker or as a guide for targeting autonomic dysregulation rather than as a direct peptide therapeutic