Compounded versions of GLP-1 receptor agonists are not FDA-approved and can increase the risk of contamination when purchased from unreliable sources
Kahleova, H., Tura, A., Klementova, M., Thieme, L., Haluzik, M., Pavlovicova, R., Hill, M., & Pelikanova, T
In West Virginia, the Public Employees Insurance Agency (PEIA) started a 1,000 person pilot program that covered GLP-1s to treat obesity beginning in 2019
Alongside compounded semaglutide and tirzepatide, they prescribe Sermorelin for growth-hormone support, NAD+ for energy and cellular repair, and tadalafil for sexual-health support all under one online medical evaluation
Acting on widely expressed GLP-1 receptors, these drugs influence multiple signaling pathways involved in metabolism, cardiovascular health, neuroprotection, and anti-inflammatory responses