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Metsera also reported MET-097i is well tolerated with a monthly dose after 12 weekly doses

The recommended schedule from clinical trials is: Weeks 1-4: 2.5 mg once weekly Weeks 5-8: 5 mg once weekly Weeks 9-12: 7.5 mg once weekly Weeks 13-16: 10 mg once weekly Weeks 17-20: 12.5 mg once weekly Week 21+: 15 mg once weekly (maximum dose) Not everyone follows this exact schedule

[39] [40] [41] It has been shown to significantly reduce blood sugar levels and increase an important metabolic enzyme for processing carbohydrates called AMPK

However, many people are now looking toward the cellular level to understand how specific molecules influence heart health