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Targeting Pyruvate Kinase M2 phosphorylation reverses aggressive cancer phenotypes

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Las ratas que recibieron metotrexato han mostrado evidencia de disminucin del estado nutricional de la colina y mayores reacciones adversas a los medicamentos debido a la disfuncin heptica (12, 124)

With the encouraging results of cancer immunotherapy in recent years, more investigation into the impact of glutamine metabolism on immune cell function in the cancer microenvironment could lead to the discovery of new targets and therapeutic approaches

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