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How Tirzepatide Supports Weight Loss and Overall Health Tirzepatide works by reducing appetite , helping individuals feel full longer and consume fewer calories

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Damluji, MD, PhD, MBA Published Mar 29, 2025 The SOUL trial, published in The New England Journal of Medicine on March 29, 2025, provides new evidence that once-daily oral semaglutide reduces the risk of major adverse cardiovascular events in adults with type 2 diabetes and a history of atherosclerotic cardiovascular disease, chronic kidney disease, or both

Cognitive and stroke-recovery claims should be read as hypotheses , not established outcomes the cognitive effects in particular should not be overstated

Most patients find it best to limit these to very small amounts or occasional treats rather than daily staples