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[Abstract]2022 Dec;9(34):e2203088

This dependency renders cells sensitive to fluctuations in extracellular cystine supply and positions system xc as a key metabolic checkpoint linking nutrient availability to oxidative stress responses and ferroptotic susceptibility

The discovery and application of agents like DRP-104 open up new avenues and possibilities for the development of more effective cancer treatment strategies

Decreased inflammatory cytokine production of antigen-specific CD4(+) T cells in NMDA receptor encephalitis

Avoid combining in the same application with strong acids (high-concentration AHA or BHA) because pH extremes can destabilize the copper complex