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[19] [20] However, existing NICE guidance on the management of obesity and type 2 diabetes including guidance on approved GLP-1 receptor agonists provides a relevant framework for understanding how such agents are evaluated and monitored within the NHS

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Many of these studies found interrelationships among oat or beta-glucan consumption with obesity, adiposity, appetite hormones, anthropometrics, percent body fat, BMI, lipid profile, satiety perception, stomach emptying, gut hormones, gut microbiota, and short-chain fatty acids [49]

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The use of sulphonylureas, glinides or thiazolidinediones to manage type 2 diabetes is associated with a typical weight gain of 25 kg [52], but a randomised controlled comparison of acarbose and glibenclamide as monotherapy in 96 patients with diabetes found no weight changes associated with acarbose therapy [32]