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Chronic NF-B activation in the gut drives the inflammatory cascades associated with inflammatory bowel disease (IBD), and KPVs ability to suppress this pathway at the tissue level is its primary research value

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Prinz et al., 2003) or a stochastic conversion of an intrinsic CNS protein, protein misfolding pathology is thought to propagate via interconnected pathways (Jucker and Walker, 2018

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