Both DPP-4 inhibitors and GLP-1 RAs have demonstrated safety in robust cardiovascular outcome trials, while several GLP-1 RAs have been shown to significantly reduce the risk of major adverse cardiovascular events in persons with T2DM with pre-existing cardiovascular disease (CVD)
Slower dose titration The standard dose escalation schedule for GLP-1 medications moves patients up to the next dose every 4 weeks
Clarke, T
J Bone Miner Res 35:14151423 Khalid SI, Omotosho PA, Spagnoli A, Torquati A (2020) Association of bariatric surgery with risk of fracture in patients with severe obesity
Best Overall: Noom, $99+ Runner-up: Hers, $199+ Best Value: Shed, $149+ Best for Oral Option: Fridays, $349+ Best Access to Health Provider: Independent Wellness, prices vary GLP-1 medications work by mimicking the bodys natural GLP-1 hormone, which helps regulate blood sugar, slows gastric emptying, and signals fullness to the brain