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Data in bar plots were presented as mean standard error of the mean (s.e.m.), whereas box and violin plots displayed the median (central line) and 25th75th percentiles

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Opening a cold vial immediately can cause atmospheric moisture to condense inside, and water is the enemy of a lyophilized powder

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Br J Clin Pharmacol 52:137144 Bailey CJ, Wilcock C, Day C (1992) Effect of metformin on glucose metabolism in the splanchnic bed

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"And because [berberine] is sold as a dietary supplement, FDA approval is not required." Any effects berberine might have on weight are far smaller than you'd get from weight loss medications

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