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Patients with RET fusionpositive thyroid cancer had radioiodine-refractory disease and received at least one previous systemic therapy other than radioiodine

Wang Z, Ying Z, Bosy-Westphal A, Zhang J, Schautz B, Later W, Heymsfield SB, Mller MJ

While these processes are essential for maintaining hormonal balance, elevated enzyme activity can lead to excessive estrogen reabsorption and contribute to hormone-related diseases