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In one embodiment, a method for increasing circulating and/or intracellular levels of glutathione includes administering an effective amount of S-acetyl-glutathione (SAG) in the form of delayed-release composition to raise the circulating levels of glutathione to achieve clinically beneficial effects

93 In their model, cydD mutants had reduced trimethoprim uptake, which was reversed by deleting acrAB or by restoring GSH (74)

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