thioredoxin glutathione Schematic overview of the and glutathione/glutaredoxin The thioredoxin and glutathione redox

doi: 10.1016/S1474-4422(14)70256-X 74 FrischerJMBramowSDal-BiancoALucchinettiCFRauschkaHSchmidbauerMet al

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Browning of White Adipose Tissue Third, and perhaps most fascinating, NNMT inhibition promotes browning of white adipose tissue - the conversion of white adipocytes into beige/brown adipocytes that contain numerous mitochondria and express uncoupling protein 1 (UCP1), enabling them to dissipate energy as heat through non-shivering thermogenesis