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15 Interestingly, the majority of ASD-related gene mutations (such as MEF2C, FMR1, PTEN, TSC1, TSC2 mutations) result in enhanced gene transcription and mRNA translation, ultimately leading to an aberrant increase in the strength or number of synapses within certain neural networks

His subsequent course was one of local satellite metastases and of subsequent spread to cervical lymph nodes and parotid gland

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