Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): A randomized, placebo-controlled, phase 3 extension study

Dietary recommendations include: Eating smaller, more frequent meals rather than large portions, which can overwhelm the slowed digestive system Increasing dietary fibre gradually through fruits, vegetables, whole grains, and legumes to support regular bowel movements and potentially benefit diverticular disease Maintaining adequate hydration aim for 6-8 glasses of water daily, particularly important if experiencing diarrhoea or constipation Limiting high-fat, fried, and spicy foods that may exacerbate nausea and delayed gastric emptying Avoiding carbonated beverages if experiencing bloating or discomfort Eating slowly and chewing thoroughly to aid digestion Lifestyle measures that support gastrointestinal health include regular physical activity, which promotes gut motility and can help prevent constipation
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Baseline labs, follow-up testing, and contraindication screening (including cancer history) are all part of responsible growth hormone peptide therapy
January 6 2015;162(1):3545