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Malhotra A, Grunstein RR, Fietze I, et al

Oral formulations taken on an empty stomach still require the 30-minute fasting window before and after dosing, which can be tricky during travel meals

Dan Skovronsky, chief scientific officer and president of Lilly Immunology, said that the company was "very pleased" with the safety and efficacy of orforglipron as seen in trials so far

The new peptide, however, turned out to slow down the stomach's processing of food and cause weight loss (Winkler, Cohen)