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When combined with medications that alter gastric motility, risk stratification becomes essential

Changes in cardiometabolic risk markers from baseline to 12 months were evaluated including blood pressure, fasting glucose, HbA1c, total cholesterol, LDL-cholesterol, HDL-cholesterol and triglycerides

"These medications are a breakthrough for clinically significant weight loss," Kanwar Kelley, MD and chief executive officer of Side Health (1), told Healthline

In May 2025, CVS Caremark announced that anti-obesity (AOM) tirzepatide (sold as Zepbound) would be removed from its preferred formulary effective July 1, 2025, with AOM semaglutide (sold as Wegovy) designated as the preferred alternative