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GLP-1s like semaglutide and tirzepatide are FDA-approved for weight loss and diabetes, so these are the safest bet legally

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Side Effect Profile and Tolerability Both compounds share a similar primary side effect profile, largely centered on the gastrointestinal system

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Other Double Agonists and Triple Agonist Beyond tirzepatide, pharmaceutical companies have developed additional dual receptor agonists targeting GLP-1 and glucagon (GCG) as well as triple receptor agonists