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Sexual dysfunction Diabetes-induced neuropathy, vascular damage, and endocrine disruption are major contributors to male sexual dysfunction, a common complication affecting approximately 90% of diabetic men [67,68,69]

Phytochemicals such as, the Resveratrol (3,4,5-trihydroxy stilbene) and the Curcuminoids (with , -unsaturated carbonyl groups) are potential inducers of HO-1 expression through Nrf2/ antioxidant-responsive element (ARE) pathway 471,472