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The mechanism of action involves several key processes: Stimulating insulin secretion from pancreatic beta cells in response to elevated blood glucose Suppressing glucagon release , which reduces glucose production by the liver Slowing gastric emptying , leading to more gradual absorption of nutrients Reducing appetite through effects on brain centres that control satiety Ozempic is administered as a once-weekly subcutaneous injection , typically starting at 0.25 mg and gradually increasing to maintenance doses of 0.5 mg, 1 mg or 2 mg, depending on individual response and tolerability

Psychoneuroendocrinology 36, 228239 (2011)

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