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Steroids mimic hormones directly, acting as a replacement without stimulating the body to release its own hormones

Peptide therapy offered something different: the ability to work with the bodys own biology to promote genuine, lasting improvement

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10.1016/j.cell.2016.11.018 388 SanadaK.NakajimaS.KurokawaS.Barcel-SolerA.IkuseD.HirataA.et al

Copper normally travels bound to proteins like ceruloplasmin, but GHKs tripeptide chain has a particularly high affinity for copper (II) ions, forming a stable chelate complex that can shuttle copper efficiently into cells