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iScience 26 , 106848 (2023)
Potential side effects Since the active molecule is the same, side effects overlap: Nausea or queasiness, especially when you start or increase dose Diarrhea or constipation as your digestive system adapts Occasional fatigue or headache Rare injection-site reactions (not an issue with drops) You may find GI symptoms a bit milder with oral use, or you might notice them more if you take drops on a full stomach
50 Danuglipron showed a dose-proportional increase in exposure at steady state with reductions in the mean daily glucose, fasting plasma glucose, and glycated hemoglobin (HbA1c) compared to baseline and placebo
Patients diagnosed with diabetes are initiating GLP-1 treatment more quickly than ever before Since 2021, the average time between a diabetes diagnosis and the initiation of a GLP-1 therapy has decreased by about one month, underscoring how quickly these drugs have moved to the forefront of care
Ultimately, causality cannot be inferred from these observational findings
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