However, the cell death, proteasome inhibition and apoptosis were observed using 1 mM ibuprofen, which is significantly higher than the peak ibuprofen concentrations found in human blood (58.4 g/mL or 283.09 M) after high doses of ibuprofen 39 , and as such may not be physiologically relevant
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389 The combination of CXCR4-targeted p53 mRNA nanoparticles and PD1 reprogrammed the molecular and cell components of the TME in p53-null orthotopic and ectopic HCC models
5,6-Dihydroxyindole eumelanin content in human skin with varying degrees of constitutive pigmentation