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Biochemically, different structures are grouped together under B complex on the basis of their natural occurrence in same type of food and solubility in water

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1,6,7 Options include SGLT-2 inhibitors, which also have cardiorenal protective benefits, or sulfonylureas

Hepatitis/Elevated liver enzymes/Jaundice -Diabetic retinopathy problems: Changes in vision in those with type II diabetes, particularly vision problems may worsen in those with a history of diabetic retinopathy Severe gastrointestinal disease - may cause gastrointestinal disease

Monitoring: Consider periodic testosterone and estradiol testing