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The narrative review on supplements during GLP-1 therapy A narrative review published in a peer-reviewed journal specifically examined dietary supplement considerations during GLP-1 receptor agonist treatment

Fluoxetine also promotes cytochrome c oxidase and glutamate dehydrogenase activity in presynaptic mitochondria of rat hippocampus (160, 268), and inhibits multiple other enzymes in mitochondria (181)

Given the increased risk of HDP in pregnant women with MTHFR TT genotype, and the blood pressure-lowering effect of riboflavin in non-pregnant adults with this genotype, it is worth exploring further whether targeted supplementation with riboflavin in pregnancy has benefits as an effective preventive strategy to reduce the risk of HDP and decrease the burden of related adverse pregnancy outcomes in genetically at-risk women

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