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We additionally summarize the evidence by domain and certainty level in a structured Supplementary Table 6, explicitly separating relatively robust short-term metabolic evidence from more exploratory reproductive and periconception safety findings

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Meta-Analyses: Reviews of multiple studies confirm that selenium supplementation reduces both TPOAb and thyroglobulin antibodies (TgAb), markers of autoimmune thyroid disease

PMCID: PMC8228050