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Diabetes alters the expression profiles of numerous non-coding RNAs in sperm, especially miRNAs, which may influence spermatogenesis and fertility [199]

One of these antioxidant defense systems is the glutathione antioxidant pathway, which includes the enzymes GPx, GST and GR

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These effects were associated with the inhibition of NF-B nuclear translocation and reduced phosphorylation of B and mitogen-activated protein kinases, including p38, extracellular signal-regulated kinases 1 and 2 (Erk 1/2), and c-Jun N-terminal kinase (282)