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These medications are contraindicated in patients with: Personal history of medullary thyroid carcinoma Family history of medullary thyroid carcinoma Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) For patients with standard hypothyroidism (typically autoimmune thyroiditis or post-ablation), these contraindications do not apply

Although locally invasive, the risk of tumour metastasis is less than 5%

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In the day of the experiment, cells were stained with 10 M DCFH-DA at 37 C for 30 min, then were treated as described above for 4 h

Storage: 2 - 8 C